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Changes in fecal microbiota composition following 4 and 8 weeks of calcifediol (25D3) supplementation. (A) α-Diversity measured by Chao1, Faith’s PD, and Shannon Index. (B) PCoA plot of DEICODE distances for the fecal microbiome. Significance of changes in β-diversity by timepoint was calculated using PERMANOVA, adjusted for subject. (C) Genus level taxonomic profiles at baseline, week 4 and week 8 after 25D3 supplementation.
