Table 2.
Cox regression for analysis of the risk of death in the 60-month period of follow-up, according to the baseline characteristics of the patients
| Unadjusted HR (95% CI) | P-value | Adjusted HR (95% CI) | P-value | |
|---|---|---|---|---|
| Male | 0.81 (0.74 – 0.90) | <0.0001 | 0.96 (0.83 – 1.11) | 0.58 |
| Age (years) | 1.04 (1.03 – 1.04) | <0.0001 | 1.03 (1.03 – 1.04) | <0.0001 |
| Non-white race/ethnicity | 0.94 (0.85 – 1.04) | 0.25 | - | - |
| Diabetes | 1.23 (1.12 – 1.36) | <0.0001 | 1.29 (1.11 – 1.50) | 0.001 |
| Public healthcare | 1.01 (0.91 – 1.11) | 0.87 | - | - |
| Early referral | 0.62 (0.55 – 0.70) | <0.0001 | 0.88 (0.74 – 1.05) | 0.16 |
| First dialysis in hospital | 1.62 (1.43 – 1.83) | <0.0001 | 1.29 (1.05 – 1.58) | 0.016 |
| Catheter | 2.01 (1.79 – 2.26) | <0.0001 | 1.22 (1.03 – 1.44) | 0.023 |
| BMI (Kg/m2) | 0.97 (0.96 – 0.98) | <0.0001 | 0.98 (0.96 – 0.99) | 0.015 |
| Haemoglobin (g/dL) | 0.87 (0.85 – 0.90) | <0.0001 | 0.95 (0.91 – 0.98) | 0.004 |
| TSAT ≥ 20% | 0.67 (0.60 – 0.75) | <0.0001 | 0.80 (0.69 – 0.92) | 0.002 |
| Ferritin ≥ 200 ng/mL | 1.09 (0.98 – 1.22) | 0.12 | - | - |
| Erythropoietin use | 0.96 (0.87 – 1.05) | 0.37 | - | - |
| BUN (mg/dL) | 0.99 (0.99 – 0.99) | <0.0001 | 1.00 (0.99 – 1.00) | 0.13 |
| Serum albumin (g/L) | 0.92 (0.91 – 0.93) | <0.0001 | 0.96 (0.95 – 0.98) | <0.0001 |
| Potassium (mEq/L) | 0.98 (0.93 – 1.03) | 0.48 | - | - |
| Phosphorus (mg/dL) | 0.89 (0.86 – 0.92) | <0.0001 | 1.00 (0.95 – 1.06) | 0.92 |
| Corrected calcium (mg/L) | 1.02 (0.99 – 1.06) | 0.14 | - | - |
| iPTH (per 100 pg/mL) | 0.95 (0.94 – 0.96) | <0.0001 | 1.00 (0.98 – 1.02) | 0.81 |
| ALP (per 100 UI/L) | 1.09 (1.06 – 1.12) | <0.0001 | 1.09 (1.03 – 1.16) | 0.005 |
| Pre-HD SBP (mmHg) | 1.00 (0.99 – 1.00) | 0.34 | - | - |
| Pre-HD DBP (mmHg) | 0.98 (0.98 – 0.99) | <0.0001 | 1.00 (0.99 – 1.01) | 0.89 |
| Lean mass (%) | 0.99 (0.98 – 0.99) | <0.0001 | 1.00 (0.99 – 1.00) | 0.33 |
| Fat mass (%) | 1.00 (0.99 – 1.00) | 0.51 | - | - |
| Fluid overload | 1.88 (1.66 – 2.14) | <0.0001 | 1.47 (1.27 – 1.71) | <0.0001 |
HR hazard ratio; CI confidence interval; BMI body mass index; TSAT transferrin saturation; BUN blood urea nitrogen; iPTH intact parathyroid hormone; ALP alkaline phosphatase; HD haemodialysis; SBP systolic blood pressure; DBP diastolic blood pressure