Table 3.

Subdistribution hazard ratio (sHR) using the Fine-Gray method for analysis of the risk of death in the 60-month period of follow-up, according to the baseline characteristics of the patients

	Unadjusted sHR (95% CI)	P-value	Adjusted sHR (95% CI)	P-value
Male	0.83 (0.76 – 0.92)	0.0002	0.96 (0.82 – 1.11)	0.57
Age (years)	1.04 (1.03 – 1.04)	<0.0001	1.03 (1.03 – 1.04)	<0.0001
Non-white race/ethnicity	0.96 (0.87 – 1.06)	0.41	-	-
Diabetes	1.32 (1.20 – 1.45)	<0.0001	1.31 (1.12 – 1.53)	0.0006
Public healthcare	1.08 (0.98 – 1.19)	0.14	-	-
Early referral	0.72 (0.65 – 0.81)	<0.0001	0.88 (0.73 – 1.05)	0.15
First dialysis in hospital	1.58 (1.40 – 1.79)	<0.0001	1.31 (1.07 – 1.61)	0.009
Catheter	1.77 (1.58 – 1.99)	<0.0001	1.13 (0.96 – 1.34)	0.14
BMI (Kg/m2)	0.97 (0.96 – 0.98)	<0.0001	0.98 (0.96 – 0.99)	0.008
Haemoglobin (g/dL)	0.88 (0.86 – 0.91)	<0.0001	0.96 (0.92 – 0.99)	0.014
TSAT ≥ 20%	0.70 (0.63 – 0.78)	<0.0001	0.81 (0.70 – 0.94)	0.005
Ferritin ≥ 200 ng/mL	1.08 (0.96 – 1.20)	0.19	-	-
Erythropoietin use	0.97 (0.88 – 1.06)	0.49	-	-
BUN (mg/dL)	0.99 (0.99 – 1.00)	<0.0001	1.00 (0.99 – 1.00)	0.22
Serum albumin (g/L)	0.93 (0.92 – 0.94)	<0.0001	0.97 (0.95 – 0.98)	0.0002
Potassium (mEq/L)	1.01 (0.96 – 1.06)	0.69	-	-
Phosphorus (mg/dL)	0.90 (0.87 – 0.93)	<0.0001	1.00 (0.95 – 1.06)	0.99
Corrected calcium (mg/L)	1.03 (1.00 – 1.06)	0.067	1.01 (0.96 – 1.06)	0.67
iPTH (per 100 pg/mL)	0.96 (0.95 – 0.98)	<0.0001	1.00 (0.98 – 1.02)	0.89
ALP (per 100 UI/L)	1.09 (1.06 – 1.12)	<0.0001	1.08 (1.02 – 1.14)	0.007
Pre-HD SBP (mmHg)	1.00 (1.00 – 1.00)	0.67	-	-
Pre-HD DBP (mmHg)	0.98 (0.98 – 0.99)	<0.0001	1.00 (0.99 – 1.01)	0.96
Lean mass (%)	0.99 (0.98 – 0.99)	<0.0001	1.00 (0.99 – 1.00)	0.17
Fat mass (%)	1.00 (1.00 – 1.01)	0.26	-	-
Fluid overload	1.93 (1.72 – 2.17)	<0.0001	1.50 (1.29 – 1.74)	<0.0001

CI confidence interval; BMI body mass index; TSAT transferrin saturation; BUN blood urea nitrogen; iPTH intact parathyroid hormone; ALP alkaline phosphatase; HD haemodialysis; SBP systolic blood pressure; DBP diastolic blood pressure