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. 2007 Oct 17;2007(4):CD005114. doi: 10.1002/14651858.CD005114.pub2

7. Clinical Relevance Table: Summary Meta‐analysis table: adverse events.

Outcome # patients (#trials) Event rate (placebo) Event rate (treated) Relative risk Absolute risk dif NNH
Adverse Events (mild/moderate): Acne 657 (4) 56/326 (17.2%) 123/331 (37.2%) 2.2 0.2 5
95% confidence interval       1.65 to 2.83 0.13 to 0.26  
Adverse Events (mild/moderate): Menstrual Change 276 (3) 5/137 (3.6%) 6/139 (4.3%) 1.2 0.1 not statistically significant
95% confidence interval       0.38 to 3.77 ‐0.04 to 0.05