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. 2022 Jan 11;77(3):854–856. doi: 10.1093/jac/dkab472

Table 1.

Patients retreated with remdesivir

Comorbidities Age (years) Gender Remdesivir treatment Days of therapy Days between treatment Room air saturation at admission (%) Maximal oxygen requirement Days of steroid therapy Hospitalization outcomes
Non-immunosuppressed
 asthma, CAD, CKD, HTN 92 male initial 5 9 93 2 L 10 discharged on RA
retreatment 5 86 5 L 5
 CAD, CHF, COPD, DM, DVT, HL, iron deficiency anaemia, obesity, TIA 77 female initial 5 14 87 3 L 5 discharged on RA
retreatment 5 94 2 L 10
 Angelman syndrome, chronic aspiration, chronic hypoxic respiratory failure (on oxygen at night), obesity, seizures 40 male initial 5 10 84 4 L 10 discharged on oxygen
retreatment 2 88 6 L 5
 DM, HTN, hypothyroidism, NHL in remission 55 female initial 5 106 92 3 L 0 discharged on RA
retreatment 3 89 RA 1
139
retreatmenta 5 90 3 L 6b
 CHF, COPD on oxygen, CVA, DM, DVT/PE, HTN, NSTEMI 72 female initial 5 27 100 MV 8 deceased
retreatment 2 99 MV 2
Immunosuppressed
 bullous pemphigoid on rituximab, CKD, COPD, DM 62 male initial 3 16 92 2 L 10 discharged home on RA
retreatment 5 85 HFNC 10b
 BOLT, ILD 32 female initial 10 10 88 2 L 0c discharged home on oxygen
retreatment 2 90 1 L 0c
 CKD, metastatic colon cancer 48 male initial 5 15 98 RA 0 deceased
retreatment 2 100 3 L 0
 follicular lymphoma 49 male initial 5 49 97 4 L 14 discharged home on oxygen
retreatment 5 98 MV taper for new HLH
 lymphoma, DVT 72 female initial 2 36 94 RA 2 deceased
retreatment 5 70 4 L 5
 AML, fungal pneumonia, Staphylococcus epidermidis endocarditis 40 male initial 5 9 89 4 L 11 deceased
retreatment 5 MV MV 11
 kidney transplant 53 male initial 4 15 85 3 L 4 deceased
retreatment 2 50 MV 10
 atrial fibrillation, NHL on rituximab, CKD, HTN 84 male initial 3 20 90 RA 0 discharged on RA
retreatment 5 88 3 L 5

BOLT, bilateral orthotopic lung transplantation; CAD, coronary artery disease; CHF, chronic heart failure; CKD, chronic kidney disease; CVA, cerebrovascular accident; DM, diabetes mellitus; DVT, deep-vein thrombosis; HFNC, high-flow nasal cannula; HL, hyperlipidaemia; HLH, haemophagocytic lymphohistiocytosis; HTN, hypertension; ILD, interstitial lung disease; MV, mechanical ventilation; NHL, non-Hodgkin’s lymphoma; NSTEMI, non-ST-elevation myocardial infarction; PE, pulmonary embolism; RA, room air; TIA, transient ischaemic attack.

a

Patient received third treatment of remdesivir.

b

Patient received prednisone taper after initial steroid treatment.

c

Patient was on chronic prednisone due to recent transplant status.