Table 1.
Comorbidities | Age (years) | Gender | Remdesivir treatment | Days of therapy | Days between treatment | Room air saturation at admission (%) | Maximal oxygen requirement | Days of steroid therapy | Hospitalization outcomes |
---|---|---|---|---|---|---|---|---|---|
Non-immunosuppressed | |||||||||
asthma, CAD, CKD, HTN | 92 | male | initial | 5 | 9 | 93 | 2 L | 10 | discharged on RA |
retreatment | 5 | 86 | 5 L | 5 | |||||
CAD, CHF, COPD, DM, DVT, HL, iron deficiency anaemia, obesity, TIA | 77 | female | initial | 5 | 14 | 87 | 3 L | 5 | discharged on RA |
retreatment | 5 | 94 | 2 L | 10 | |||||
Angelman syndrome, chronic aspiration, chronic hypoxic respiratory failure (on oxygen at night), obesity, seizures | 40 | male | initial | 5 | 10 | 84 | 4 L | 10 | discharged on oxygen |
retreatment | 2 | 88 | 6 L | 5 | |||||
DM, HTN, hypothyroidism, NHL in remission | 55 | female | initial | 5 | 106 | 92 | 3 L | 0 | discharged on RA |
retreatment | 3 | 89 | RA | 1 | |||||
139 | |||||||||
retreatmenta | 5 | 90 | 3 L | 6b | |||||
CHF, COPD on oxygen, CVA, DM, DVT/PE, HTN, NSTEMI | 72 | female | initial | 5 | 27 | 100 | MV | 8 | deceased |
retreatment | 2 | 99 | MV | 2 | |||||
Immunosuppressed | |||||||||
bullous pemphigoid on rituximab, CKD, COPD, DM | 62 | male | initial | 3 | 16 | 92 | 2 L | 10 | discharged home on RA |
retreatment | 5 | 85 | HFNC | 10b | |||||
BOLT, ILD | 32 | female | initial | 10 | 10 | 88 | 2 L | 0c | discharged home on oxygen |
retreatment | 2 | 90 | 1 L | 0c | |||||
CKD, metastatic colon cancer | 48 | male | initial | 5 | 15 | 98 | RA | 0 | deceased |
retreatment | 2 | 100 | 3 L | 0 | |||||
follicular lymphoma | 49 | male | initial | 5 | 49 | 97 | 4 L | 14 | discharged home on oxygen |
retreatment | 5 | 98 | MV | taper for new HLH | |||||
lymphoma, DVT | 72 | female | initial | 2 | 36 | 94 | RA | 2 | deceased |
retreatment | 5 | 70 | 4 L | 5 | |||||
AML, fungal pneumonia, Staphylococcus epidermidis endocarditis | 40 | male | initial | 5 | 9 | 89 | 4 L | 11 | deceased |
retreatment | 5 | MV | MV | 11 | |||||
kidney transplant | 53 | male | initial | 4 | 15 | 85 | 3 L | 4 | deceased |
retreatment | 2 | 50 | MV | 10 | |||||
atrial fibrillation, NHL on rituximab, CKD, HTN | 84 | male | initial | 3 | 20 | 90 | RA | 0 | discharged on RA |
retreatment | 5 | 88 | 3 L | 5 |
BOLT, bilateral orthotopic lung transplantation; CAD, coronary artery disease; CHF, chronic heart failure; CKD, chronic kidney disease; CVA, cerebrovascular accident; DM, diabetes mellitus; DVT, deep-vein thrombosis; HFNC, high-flow nasal cannula; HL, hyperlipidaemia; HLH, haemophagocytic lymphohistiocytosis; HTN, hypertension; ILD, interstitial lung disease; MV, mechanical ventilation; NHL, non-Hodgkin’s lymphoma; NSTEMI, non-ST-elevation myocardial infarction; PE, pulmonary embolism; RA, room air; TIA, transient ischaemic attack.
Patient received third treatment of remdesivir.
Patient received prednisone taper after initial steroid treatment.
Patient was on chronic prednisone due to recent transplant status.