Table 1.
Clinical characteristics of patient with and without COVID-19
| Patients characteristics | Overall | COVID-19 | Non COVID-19 | p value |
|---|---|---|---|---|
| Number | 370 | 194 | 176 | |
| Age, media (m-M) | 59 (18–87) | 60 (20–83) | 57 (18–87) | 0.09 |
| Gender | ||||
| Male, N (%) | 277 (74.9) | 153 (78.9) | 124 (70.5) | 0.63 |
| Female, N (%) | 93 (25.1) | 41 (21.1) | 52 (29.6) | 0.63 |
| Time from hospital admission to ICU | 6 (± 20) | 4 (± 10) | 8 (± 23) | 0.1 |
| Comorbidities | ||||
| Chronic heart disease, N (%) | 99 (26.8) | 32 (16.5) | 67 (38.7) | < 0.001 |
| Hypertension, N (%) | 166 (44.9) | 93 (48) | 73 (41.5) | 0.25 |
| CKD, N (%) | 21 (5.7) | 7 (3.6) | 14 (8) | 0.11 |
| Chronic liver disease, N (%) | 28 (7.6) | 6 (3.1) | 22 (12.5) | 0.006 |
| Chronic neurological disease, N (%) | 39 (10.5) | 11 (5.7) | 28 (15.9) | 0.002 |
| Cancer, N (%) | 26 (7.0) | 10 (5.2) | 16 (9.1) | 0.2 |
| Immunodefic/hematological/SOT, N (%) | 38 (10.3) | 22 (11.3) | 16 (9.1) | 0.59 |
| Lung disease, N (%) | 44 (11.9) | 18 (9.3) | 26 (14.8) | 0.14 |
| DM, N (%) | 67 (18.1) | 41 (21.1) | 26 (14.8) | 0.15 |
| Obesity, N (%) | 61 (16.5) | 44 (22.7) | 17 (9.7) | 0.001 |
| Therapy during ICU stay | ||||
| Mechanical ventilation, N (%) | 345 (93.2) | 187 (96.4) | 158 (89.8) | 0.02 |
| Haemodyalisis, N (%) | 54 (14.6) | 39 (20.1) | 15 (8.5) | 0.003 |
| Immunosoppressive therapy, N (%) | 142 (38.4) | 120 (61.9) | 22 (12.5) | < 0.001 |
| Antibiotics/antifungals, N (%) | 320 (86.5) | 172 (88.7) | 148 (84.1) | 0.26 |
| LOS in ICU, media (SD) | 23 (± 24) | 22 (± 20) | 25 (± 27) | 0.24 |
| Outcome | ||||
| Death in ICU, N (%) | 138 (37.3) | 69 (35.6) | 69 (39.2) | 0.54 |
Differences statistically significant are given in bold
ICU intensive care unit, CKD chronic kidney diseases, SOT solid organ transplantation, LOS length of stay, SD standard deviation