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. 2022 Feb 23;10(1):e02560-21. doi: 10.1128/spectrum.02560-21

TABLE 2.

Immunological profile of the transfused convalescent plasma unitsa

Specific antibody IgG IgM IgA
Anti-spike, median (min-max) (μg/mL for IgG, EU/mL for IgM and IgA) 7.7 (0.1–112.1) 3.0 (0–106.6) 2.9 (0–24.7)
Anti-RBD, median (min-max) (μg/mL for IgG, EU/mL for IgM and IgA) 2.7 (0.1–83.9) 2.9 (0–27.7) 2.6 (0–23.5)
Anti-nucleocapsid, median (min-max) (EU/mL for IgG, IgM, and IgA) 0.52 (0.0–8.67) 1.3 (0–10.0) 0 (0–2.3)

aAll units were also screened by the commercial Abbott assay which measures IgG to nucleocapsid but is reported as signal to cutoff values. Per manufacturer recommendation, signal to cutoff values of 1.4 or greater were used to screen. Thirty-nine of 42 paired units screened had signal to cutoff values of 1.4 or greater, with range of transfused units from 2.29 to 9.33.