Table 2.
Comparison of Surgical Data and Long-Term Survival for the Appendicular and Axial Cohorts
| Patient Characteristic | Total | Appendicular | Axial | Other | P |
| No. of patients | 4,430 | 3,435 | 810 | 185 | |
| Surgical treatment | <0.001 | ||||
| No surgery | 755 (17.04) | 470 (13.68) | 225 (27.78) | 60 (32.43) | |
| Surgery | 3,669 (82.82) | 2,959 (86.14) | 585 (72.22) | 125 (67.57) | |
| Unknown | 6 (0.14) | 6 (0.17) | 0 (0.00) | 0 (0.00) | |
| Radiation therapy | <0.001 | ||||
| None | 4,147 (93.61) | 3,321 (96.69) | 667 (82.35) | 159 (85.95) | |
| Preoperative | 31 (0.70) | 14 (0.41) | 13 (1.60) | 4 (2.16) | |
| Postoperative | 182 (4.11) | 454 (1.57) | 110 (13.58) | 18 (9.73) | |
| Both or intraoperative | 8 (0.18) | 4 (0.12) | 4 (0.49) | 0 (0.00) | |
| Unknown | 62 (1.40) | 42 (1.22) | 16 (1.98) | 4 (2.16) | |
| Chemotherapy | <0.001 | ||||
| No (0) | 862 (19.46) | 542 (15.78) | 261 (32.22) | 59 (31.89) | |
| Yes (1) | 3,500 (79.01) | 2,851 (83.00) | 525 (64.81) | 124 (67.03) | |
| Unknown (2) | 68 (1.53) | 42 (1.22) | 24 (2.96) | 2 (1.08) | |
| Treatment combination | <0.001 | ||||
| No treatment | 274 (6.19) | 152 (4.43) | 96 (11.85) | 26 (14.05) | |
| Isolated surgery | 625 (14.11) | 445 (12.95) | 157 (19.38) | 23 (12.43) | |
| Isolated radiation | 6 (0.14) | 1 (0.03) | 3 (0.37) | 2 (1.08) | |
| Isolated chemotherapy | 570 (12.87) | 381 (11.09) | 152 (18.77) | 37 (20.00) | |
| Surgery and radiation | 69 (1.56) | 16 (0.47) | 40 (4.94) | 13 (7.03) | |
| Surgery and chemotherapy | 2,741 (61.87) | 2,385 (69.43) | 280 (34.57) | 76 (41.08) | |
| Chemotherapy and radiation | 2 (0.05) | 1 (0.03) | 1 (0.12) | 0 (0.00) | |
| Surgery, radiation, and chemotherapy | 143 (3.23) | 54 (1.57) | 81 (10.00) | 8 (4.32) | |
| Survival | <0.001 | ||||
| 1-yr survival (%) | 87.1 | 91.17 | 74.22 | 67.33 | |
| 5-yr survival (%) | 60.17 | 64.43 | 45.97 | 42.57 | |
| 10-yr survival (%) | 53.92 | 58.58 | 38.27 | NA |
No statistically significant difference exists between the era groups for the above variables, within the appendicular or axial cohorts.
Significance set at <0.05.