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miR-122 annealing to the HCV genome. An Ago:miR-122 complex binds to two sites (Site-1 and Site-2) on the 5′UTR of the HCV genome and promote viral propagation. The miR-122 binding pattern and sequence of nucleotides 1 to 46 of the 5′UTR of hepatitis C virus genome and miR122 annealing to it are shown.
