Table 2. Table comprising data compiled from published case reports/case series on bradyarrhythmia's seen in patients with COVID-19 infection.
n/a: Data not available, HTN: Hypertension, DM: Diabetes mellitus, HLD: Hyperlipidemia, CVA: Cerebrovascular accident, LVEF: Left ventricular ejection fraction, CHB: Complete heart block, PPM: Permanent pacemaker, AV: Atrioventricular, CAD: Coronary artery disease, AS: Aortic stenosis, BMI: Body mass index, CMP: Cardiomyopathy, COPD: Chronic obstructive pulmonary disease, CHF: Congestive heart failure, MI: Myocardial infarction, OSA: Obstructive sleep apnea, CVD: Cardiovascular diseases, aVL: Augmented vector left, RBBB: Right bundle branch block, LAFB: Left anterior fascicular block, LPFB: Left posterior fascicular block, LAHB: Left anterior hemiblock
| Reference No. | Age | Gender | Comorbidities | LVEF and Troponin | Intubation | Day since admission when EKG changes noted | Baseline EKG on Admission | EKG Changes | Pacemaker | Outcome |
| [4] | 69 | Female | HTN, DM, CVA, Asthma, HLD | Normal | No | 8 | Normal | 2:1 AV Block, sinus arrest | No | Discharged |
| [4] | 83 | Female | HTN, HLD | Normal LVEF, Elevated Trop | No | 8 | Normal | Sinus Arrest | No | Discharged |
| [5] (Case series of 7 Patients) | n/a | Males 3/7 Females 4/7 | HTN 5/7, HLD 1/7, DM 6/7 Hepatic Disease/Cirrhosis 2/7 CVD 1/7, CKD 1/7 | Normal LVEF in all patients Troponin elevated in 2/7 | n/a | n/a | First Degree AV Block 1/7 RBBB 2/7, LAHB+RBBB 1/7 | CHB 2/7, Sinus Bradycardia and CHB with 1/7, 2:1 AV block 1/7, Sinus pauses/sinus arrest 3/7 | Temporary Pacemaker 3/7 Permanent Pacemaker 4/7 | Patients died 5/7 Discharged 2/7 |
| [6] | 34 | Male | Bipolar Disorder, Hypothyroidism | Normal | Yes | n/a | Normal | Sick sinus syndrome | Permanent Pacemaker | Discharged |
| [7] | 70 | Female | None | Normal | Yes | 2 | Normal | Sinus Bradycardia | No | Discharged |
| [7] | 81 | Male | Ascending Aortic Aneurysm, OSA HTN | Normal LVEF, Elevated Troponin | Yes | 4 | Normal | Sinus Bradycardia | No | Discharged |
| [8] | 67 | Male | HTN, HLD, Ex-Smoker | Normal LVEF, Elevated Troponin | Yes | 7 | Sinus bradycardia with first degree AV Block | Sinus pauses | Transcutaneous pacing only | Discharged |
| [9] (Case series of 7 Patients) | n/a | Males 4/7 Females 3/7 | DM, HTN, MI 2/7 CHF 1/7 | Normal ECHO 5/7, LVEF < 50 2/7 Elevated Troponin 1/7 | n/a | 1 | n/a | CHB 5/7 Sick sinus syndrome 2/7 | PPM in 5 patients with CHB | Discharged |
| [10] | 54 | Male | n/a | Normal LVEF | Yes | 14 | Normal | CHB | No | Death while hospitalized |
| [11] | 58 | Female | HTN, DM, CHF | LVEF 45-50 %, Normal Trop | No | 5 | Normal | Sinus bradycardia | Permanent Pacemaker | Discharged |
| [12] | 72 | Female | HTN, DM | Normal LVEF, Elevated Troponin | Yes | n/a | n/a | Sinus bradycardia CHB, Pulseless arrest | Temporary Pacemaker | Discharged |
| [13] | 47 | Female | None | Normal | No | n/a | n/a | Sinus bradycardia, Sinus pauses Junctional escape rhythm with AV dissociation | No | Not admitted in hospital |
| [14] | 42 | Female | DM, BMI > 30 | Normal LVEF, Elevated Trop | No | 2 | n/a | CHB | No | Discharged |
| [14] | 62 | Male | HTN, DM, CAD, BMI > 25 | Normal LVEF, Elevated Trop | No | 1 | n/a | CHB | Temporary Pacemaker | Discharged |
| [14] | 61 | Male | HTN, BMI > 25 | Normal | No | 2 | n/a | CHB | No | Discharged |
| [14] | 64 | Male | HTN, BMI > 25 | Normal | No | 2 | n/a | CHB | No | Discharged |
| [15] | 75 | Female | None | Normal | Yes | 33 | n/a | Sinus bradycardia, Sinus pauses | Permanent Pacemaker | Discharged |
| [16] | 55 | Female | None | Normal | No | 2 | Normal | Sinus bradycardia, Sinus pauses | No | Discharged |
| [17] | 50 | Female | BMI > 30 | Normal | No | n/a | n/a | Sinus bradycardia | Permanent Pacemaker | Discharged |
| [17] | 65 | Female | HTN, DM | Normal | No | n/a | n/a | CHB | Permanent Pacemaker | Discharged |
| [17] | 43 | Female | None | Normal | No | n/a | n/a | CHB | Temporary Pacemaker | Discharged |
| [17] | 25 | Male | None | Normal | No | n/a | n/a | CHB | No | Discharged |
| [17] | 60 | Male | HTN | Normal | No | n/a | n/a | CHB | No | Discharged |
| [17] | 70 | Female | HTN | Normal | No | n/a | n/a | CHB | Permanent Pacemaker | Discharged |
| [18] | 71 | Female | Parkinson Disease, Tardive Dyskinesia DM, Bipolar Disorder | Normal | No | n/a | n/a | CHB | Permanent Pacemaker | Discharged |
| [19] | 38 | Female | None | Normal | No | n/a | n/a | Sinus bradycardia, CHB | No | Discharged |
| [20] | 48 | Male | None | Normal | No | 1 | n/a | CHB | No | Discharged |
| [21] | 36 | Male | None | Normal | No | n/a | n/a | Sinus node dysfunction, sinus pauses/ sinus node arrest | Permanent Pacemaker | Discharged |
| [22] | 44 | Male | DM | Normal | No | 1 | n/a | CHB | No | Discharged |
| [23] (Case series of 6 Patients) | n/a | Male – 3/6 Female – 3/6 | HTN – 5/6 | Normal LVEF – 5/6, EF – 45-50 % - 1/6, Normal Trop – 6/6 | No | 6, 4, 3, 4, 3, 3 | Normal 6/6 | Sinus Bradycardia 6/6 | No | Discharged |
| [24] | 41 | Male | Familial Mediterranean Fever | Normal | Yes | 5 | Normal | CHB | No | Death while hospitalized |
| [24] | 77 | Male | None | Normal | Yes | 7 | Normal | CHB, sinus pause | Temporary Pacemaker | Death while hospitalized |
| [24] | 36 | Female | n/a | LVEF 30 %, Normal Troponin | Yes | 5 | Sinus Tachycardia | CHB | No | Discharged |
| [25] | 60 | Male | HTN, Non-Ischemic Dilated CMP, COPD HLD, Cocaine abuse | LVEF-25 %, Normal Troponin | No | 1 | LBBB | High Grade AV Block w RBBB escape morphology | No | Discharged |
| [26] | 49 | Male | HTN | Normal | No | n/a | n/a | CHB | Permanent Pacemaker | Discharged |
| [27] | 41 | Male | DM | Normal | No | 2 | Normal | Paroxysmal AV block, Sinus arrest | Permanent Pacemaker | Discharged |
| [28] | 53 | Male | None | Mildly impaired LVEF, Normal Troponin | No | 7 | Normal | Type 2 AV block (Mobitz 2), CHB, High Degree AV Block | Permanent Pacemaker | Discharged |
| [29] | 23 | Male | Stage 3b Hodgkin’s Lymphoma | LVEF 35-40 %, Elevated Troponin | No | 1 | Sinus Tachycardia with RBBB | CHB | Temporary Pacemaker | Discharged |
| [30] | 74 | Female | DM | Normal Troponin | Declined by patient | n/a | RBBB w LAFB | RBBB w LPFB, 2nd Degree AV Block (Mobitz Type 2) | Declined by patient | Death while hospitalized |
| [31] | 82 | Male | HTN, CVA | Normal Troponin | Yes | 1 | Normal | CHB | No | Death while hospitalized |
| [31] | 55 | Male | None | Normal Troponin initially later becoming Elevated, RH strain of bedside ECHO | Yes | 6 | RBBB, ST depressions at inferior leads Present at baseline | 2:1 AV Block | No | Discharged |
| [31] | 43 | Male | None | Normal | Yes | 24 | Normal | CHB | No | Discharged |
| [32] | 56 | Male | DM | Normal | No | 3 | Normal | CHB | Temporary pacemaker | Discharged |
| [32] | 48 | Male | HTN | Normal | No | 5 | T wave inversions V1-V2 | CHB | No | Discharged |
| [32] | 57 | Female | None | Normal | No | n/a | Normal | CHB | Temporary Pacemaker | Discharged |
| [32] | 42 | Female | DM | Normal | No | 3 | T wave inversions lead 1, aVl and V2 | CHB | Temporary Pacemaker | Discharged |
| [33] | 55 | Male | Hypothyroidism, BMI > 30 | n/a | No | 1 | Normal | Sinus Bradycardia | No | Discharged |
| [33] | 60 | Female | None | n/a | No | 1 | Normal | Sinus Bradycardia | No | Discharged |
| [33] | 78 | Female | Hypothyroidism, CAD, HTN, HLD, BMI > 25 | n/a | No | 4 | Normal | Sinus Bradycardia | No | Discharged |
| [33] | 73 | Male | CAD, HTN, HLD, AS, BMI >35 | n/a | No | 4 | Normal | Sinus Bradycardia | No | Discharged |