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. 2022 Feb 10;18(2):e1009855. doi: 10.1371/journal.pcbi.1009855

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© 2022 Wang et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — a. Refinement of α-NADPH (yellow) in the SaDHFR:R-27 crystal structure. Green mesh (difference density) shows unsatisfied electron density. b. Overlay of α-NADPH and t-NADPH (light gray) in the SaDHFR:R-27 crystal structure. c. Refinement of t-NADPH in the SaDHFR:R-27 crystal structure.