. 2022 Feb 23;17(2):e0263683. doi: 10.1371/journal.pone.0263683

Table 4. Regression variables for lung function and health-related quality of life using handgrip strength and other co-variates.

Pre-operative variables	Predictors	B	SE_B	Adj R²	p-value
FEV₁	Pre-op HGS	0.021	0.006	0.264	<0.001
	Height	2.904	0.680	0.345	<0.001
	Comorbidity- Hypertension	0.255	0.113	0.363	0.026
	Comorbidity-Chronic Kidney Disease	0.434	0.218	0.387	0.049
FVC	Height	3.970	0.868	0.282	<0.001
	Pre-op HGS	0.027	0.007	0.375	<0.001
	Comorbidity- Hypertension	0.299	0.145	0.395	0.043
PEFR	Pre-op HGS	0.077	0.016	0.264	<0.001
	Comorbidity-IHD	1.652	0.378	0.351	<0.001
	Sex	-1.605	0.440	0.411	<0.001
	Comorbidity-Obesity	0.675	0.298	0.435	0.026
HRQoL-PCS	Body Mass Index	-0.556	0.165	0.089	0.001
	Comorbidity- Gout	-7.780	3.458	0.120	0.027
	Comorbidity- Dyslipidaemia	4.467	2.152	0.150	0.041
Physiotherapy discharge variables
FEV1	Pre-op FEV₁	0.451	0.053	0.417	<0.001
	PainCough	-0.34	0.11	0.472	0.004
	Comorbidity-Dyslipidaemia	-0.161	0.070	0.496	0.024
FVC	Pre-op FVC	0.473	0.055	0.425	<0.001
	PainCough	-0.043	0.16	0.470	0.008
	Comorbidity-Dyslipidaemia	-0.218	0.095	0.495	0.024
PEFR	Pre-op PEFR	0.434	0.065	0.264	<0.001
	PainCough	-0.135	0.042	0.314	0.002
	Employment status	0.483	0.136	0.360	<0.001
	Comorbidity-COPD	1.420	0.472	0.400	0.003
	Body Mass Index	0.041	0.020	0.423	0.040
HRQoL-PCS	Ethnicity	-6.506	1.834	0.112	<0.001
	PainCough	-0.909	0.302	0.186	0.003
HRQoL-MCS	Pre-op MCS	0.474	0.096	0.228	<0.001
	PainCough	-1.097	0.326	0.308	0.001
Pre-operative to physiotherapy discharge changes
FEV₁	Pre-op FEV₁	-6.714	2.081	0.095	0.002
	LVEF	-0.267	0.100	0.167	0.009
	PainCough	-1.143	0.460	0.216	0.015
FVC	Pre-op FVC	-6.656	1.663	0.145	<0.001
	LVEF	-0.296	0.104	0.219	0.006
	PainCough	-0.986	0.480	0.249	0.043
PEFR	Pre-op PEFR	-2.178	0.968	0.063	0.027
	Age	-0.453	0.155	0.113	0.005
	Comorbidity-COPD	-13.527	6.619	0.146	0.044
	PainCough	-1.243	0.618	177	0.048
HRQoL-PCS	Pre-op PCS	-1.894	0.222	0.383	<0.001
	Age	-0.668	0.206	0.431	0.002
	PainCough	-2.642	0.840	0.486	0.002
HRQoL-MCS	Pre-op MCS	-1.227	0.223	0.204	<0.001
	PainCough	-1.910	0.776	0.255	0.016
	ACXT	-0.190	0.081	0.294	0.020

FEV₁ –Forced expiratory volume in one second; FVC–Forced vital capacity; PEFR–Peak expiratory flow rate; HGS–Handgrip strength; HRQoL–Health-related quality of life; PCS–Physical component score; MCS–Mental component score; IHD–Ischaemic heart disease; COPD–Chronic obstructive pulmonary disease; CPBT–Cardiopulmonary by-pass time; PainCough–Chest pain during coughing, ACXT–Aortic cross-clamp time; LVEF—Left ventricular ejection fraction. B–Unstandardized coefficient; SB_E−Standard error of the coefficient.