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. 2021 Mar 30;204(12):1418–1432. doi: 10.1164/rccm.202102-0329OC

Figure 3.


Figure 3.

Mesenchymal stem/stromal cell–small extracellular vesicles (MEx) restore pulmonary myeloid cell apportion. Mass cytometry was undertaken on whole-lung samples across all experimental groups at PN7 and PN14. (A and B) The proportion of CD45+ cells at PN7 (A) and PN14 (B). (C and D) The cell proportions of alveolar macrophage (Mϕ), interstitial Mϕ, Ly6Chigh, and Ly6Clow monocyte populations at PN7 (C) and PN14 (D). Gating strategy is shown in Figure E5. Data expressed as percentage of CD45+ population. n = 4–8 per group; *P < 0.05 and $P < 0.0001 versus HYRX. HYRX = hyperoxia; NRMX = normoxia; PN = Postnatal Day.