Table 1.
Univariable and Multivariable Linear Regression Models for Sociodemographic and Microbiologic Factors Associated with RISK11 Score in the Respiratory Organisms Cohort
| Variable | N = 286 | Univariable Analysis |
Multivariable Analysis |
|||
|---|---|---|---|---|---|---|
|
β Coefficient (95% CI) |
P Value |
β Coefficient (95% CI) |
Odds Ratio (95% CI) |
P Value | ||
| Age, yr, median (IQR) | 27 (22 to 34) | 0.01 (−0.01 to 0.02) | 0.266 | — | — | — |
| BMI, kg/m2, median (IQR) | 22.5 (19.1 to 28) | 0 (−0.02 to 0.02) | 0.969 | — | — | — |
| Sex, M, n (%) | 116 (40.6) | −0.24 (−0.54 to 0.05) | 0.108 | — | — | — |
| Adenovirus, n (%) | 1 (0.4) | 4.45 (4.3 to 4.59) | <0.001 | — | — | — |
| Coronavirus (NL63, 229E, OC43, and HKU1), n (%) | 10 (3.5) | 1.3 (0.32 to 2.28) | 0.01 | 1.38 (0.39 to 2.36) | 4.0 (1.5 to 10.6) | 0.006 |
| Influenza (A, B, C, and H1N1), n (%) | 3 (1.1) | 3.57 (3.31 to 3.82) | <0.001 | 3.68 (3.42 to 3.93) | 39.6 (30.6 to 51.1) | <0.001 |
| Rhinoviruses, n (%) | 21 (7.3) | 0.8 (−0.03 to 1.64) | 0.052 | 0.88 (0.04 to 1.71) | 2.4 (1 to 5.5) | 0.039 |
| Prevalent tuberculosis, n (%) | 11 (3.9) | 0.97 (−0.49 to 2.42) | 0.192 | 1.06 (−0.4 to 2.52) | 2.9 (0.7 to 12.5) | 0.154 |
| Incident tuberculosis, n (%) | 9 (3.1) | 0.41 (−0.9 to 1.72) | 0.541 | — | — | — |
| Haemophilus influenzae, n (%) | 65 (22.7) | −0.04 (−0.38 to 0.3) | 0.808 | — | — | — |
| Klebsiella pneumoniae, n (%) | 8 (2.8) | −0.57 (−1.19 to 0.06) | 0.075 | — | — | — |
| Moraxella catarrhalis, n (%) | 18 (6.3) | 0.46 (−0.07 to 0.98) | 0.091 | — | — | — |
| Parainfluenza (types 1–4), n (%) | 1 (0.4) | 4.92 (4.77 to 5.06) | <0.001 | — | — | — |
| Respiratory syncytial virus (A or B), n (%) | 2 (0.7) | 0.57 (−0.25 to 1.4) | 0.171 | — | — | — |
| Staphylococcus aureus, n (%) | 28 (9.8) | −0.05 (−0.59 to 0.49) | 0.865 | — | — | — |
| Streptococcus pneumoniae, n (%) | 32 (11.2) | −0.22 (−0.65 to 0.22) | 0.333 | — | — | — |
Definition of abbreviations: BMI = body mass index; CI = confidence interval; IQR = interquartile range.
Odds ratios were obtained by exponentiating the β coefficients and are only shown for variables in the multivariable model.