Table 2.

Association between the Upper Respiratory Tract Microbiota Composition and Metadata in Patients with COVID-19

	Admission		Discharge/Death
	R 2	P Value	R 2	P Value
Mortality	0.026	0.005	0.024	0.002
Age	0.011	0.219	0.008	0.168
Sex	0.006	0.593	0.004	0.571
Corticosteroid	0.006	0.633	0.003	0.807
Severity-A	0.015	0.508	0.017	0.100
Lopinavir–ritonavir	0.009	0.314	0.002	0.957
Comorbidity	0.004	0.828	0.004	0.539
Antibiotics*	0.011	0.184	0.008	0.166
High-grade antibiotics	0.012	0.250	0.019	0.008

Definition of abbreviations: COVID-19 = coronavirus disease; Severity-A = severity on admission.

R², which represents the proportion of variance explained by the factor, and the P value were calculated by permutational multivariate ANOVA analysis. P values below 0.05 are in bold.

^*Duration of antibiotic use (0 if no antibiotics were taken).