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. 2021 Mar 30;204(12):1379–1390. doi: 10.1164/rccm.202103-0814OC

Table 3.

Logistic Regression Analysis of Variables Associated with Mortality

  Univariate OR (95% CI) P Value Multivariate OR (95% CI) P Value
S. parasanguinis, relative abundance 0.30 (0.13–0.66) 0.004 0.09 (0.02–0.38) 0.002
Sex (M vs. F) 1.70 (0.79–3.84) 0.185 1.93 (0.53–7.93) 0.333
Age 1.08 (1.04–1.12) <0.001 1.12 (1.06–1.21) 0.001
Lopinavir–ritonavir (yes vs. no) 0.50 (0.23–1.05) 0.071 0.59 (0.16–2.02) 0.399
Severity-A (4 vs. 3) 0.56 (0.20–1.87) 0.312 0.56 (0.11–3.14) 0.485
Severity-A (5 vs. 3) 11.73 (3.26–49.99) <0.001 19.56 (2.38–243.84) 0.010
Antibiotics* 0.79 (0.31–1.93) 0.608 0.98 (0.26–3.65) 0.980
Corticosteroid (yes vs. no) 5.78 (2.68–12.92) <0.001 1.8 (0.3–10.05) 0.504
Comorbidity (with vs. without) 3.09 (01.37–7.68) 0.009 0.97 (0.21–4.31) 0.964

Definition of abbreviations: CI = confidence interval; OR = odds ratio; S. parasanguinis = Streptococcus parasanguinis; severity-A = severity on admission.

P values below 0.05 are in bold.

*

Duration of antibiotic use. High-grade antibiotics were not included in the analysis as only one patient took high-grade antibiotics before sampling.