Table 3.
Logistic Regression Analysis of Variables Associated with Mortality
Univariate OR (95% CI) | P Value | Multivariate OR (95% CI) | P Value | |
---|---|---|---|---|
S. parasanguinis, relative abundance | 0.30 (0.13–0.66) | 0.004 | 0.09 (0.02–0.38) | 0.002 |
Sex (M vs. F) | 1.70 (0.79–3.84) | 0.185 | 1.93 (0.53–7.93) | 0.333 |
Age | 1.08 (1.04–1.12) | <0.001 | 1.12 (1.06–1.21) | 0.001 |
Lopinavir–ritonavir (yes vs. no) | 0.50 (0.23–1.05) | 0.071 | 0.59 (0.16–2.02) | 0.399 |
Severity-A (4 vs. 3) | 0.56 (0.20–1.87) | 0.312 | 0.56 (0.11–3.14) | 0.485 |
Severity-A (5 vs. 3) | 11.73 (3.26–49.99) | <0.001 | 19.56 (2.38–243.84) | 0.010 |
Antibiotics* | 0.79 (0.31–1.93) | 0.608 | 0.98 (0.26–3.65) | 0.980 |
Corticosteroid (yes vs. no) | 5.78 (2.68–12.92) | <0.001 | 1.8 (0.3–10.05) | 0.504 |
Comorbidity (with vs. without) | 3.09 (01.37–7.68) | 0.009 | 0.97 (0.21–4.31) | 0.964 |
Definition of abbreviations: CI = confidence interval; OR = odds ratio; S. parasanguinis = Streptococcus parasanguinis; severity-A = severity on admission.
P values below 0.05 are in bold.
Duration of antibiotic use. High-grade antibiotics were not included in the analysis as only one patient took high-grade antibiotics before sampling.