Figure 7. Sequential replay requires firing rate adaptation in the pyramidal cell (PC) population.

(A) Voltage traces of fitted AdExpIF (blue) and ExpIF (gray) PC models and experimental traces (green) are shown in the top panel. Insets show the f–I curves of the in vitro and in silico cells. The amplitudes of the 800-ms-long step current injections shown at the bottom were as follows: –0.04, 0.15, and 0.6 nA. For parameters of the cell models, see Table 2. (B) PC raster plot of a 10-s-long simulation with the ExpIF PC models, showing stationary activity in the top panel. PC population rate is shown below.