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Effects of PMA on signaling pathways in EL4 tumors. Immunoblots of tumor tissue for PD-1, HIF-1α, p-IκBα, and p-JNK with quantified protein band intensities corrected by controls. Animals were intraperitoneally administered with vehicle or PMA for 3 days. Bars represent the mean ± SD of quintuple mice per group. ∗P < 0.05, †P < 0.005, and ‡P < 0.001.
