FIG 1.

Hydrolysis of β-lactams by M. tuberculosis PBPs. The percentage hydrolysis represents the cumulative hydrolysis of each class of β-lactams by each protein. The penicillin subclasses of β-lactams included in this study are penicillin G, ampicillin, amoxicillin, piperacillin, and oxacillin. The cephalosporins included are cefadroxil, cefoxitin, cefotaxime, ceftriaxone, cefdinir, and cephalexin; the carbapenems included are imipenem, meropenem, doripenem, and biapenem, and the penems included are faropenem and T405. Additional details are included in Fig. S1.