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. 2022 Feb 16;2022:2240605. doi: 10.1155/2022/2240605

Figure 3.

Figure 3

SOX7 is a direct target of miR-146a in pancreatic cancer cells. (a) Predicted interacting sites between miR-146a and SOX7 were showed including wilt type and mutant type. (b) Luciferase reporter activities of wild-type SOX7 vectors were decreased by miR-146a but not miR-NC or mutant SOX7 vectors in PC cells. (c, d) miR-146a inhibits SOX7 RNA expression in Panc-1 and PCL-35 by qRT-PCR. (e, f) miR-146a inhibits SOX7 protein expression in Panc-1 and PCL-35 by western blot (∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001).