Table 2.

Number of patients reporting a change in Covid-19 related clinical symptoms.

	Baseline	Day 7	Day 14	Day 30	Day 45	Day 60	Day 75	Day 90
Fever
Add-on Group (n = 77)	43	0∗∗	0∗∗	0∗∗	0∗∗	0∗∗	0∗∗	0∗∗
SOC Group (n = 73)	55	11∗∗	4∗∗	0∗∗	0∗∗	0∗∗	0∗∗	0∗∗
Sore throat
Add-on Group (n = 77)	10	0∗∗	0∗∗	0∗∗	0∗∗	0∗∗	0∗∗	0∗∗
SOC Group (n = 73)	15	7	4∗	3∗∗	2∗∗	0∗∗	0∗∗	0∗∗
Difficulty in breathing
Add-on Group (n = 77)	64	49	18∗∗,###	10∗∗,@@@	5∗∗,###	0∗∗,###	0∗∗,###	0∗∗,###
SOC Group (n = 73)	70	49∗	19∗∗,###	10∗∗,###	7∗∗,###	0∗∗,###	0∗∗,###	0∗∗,###
Dry cough
Add-on Group (n = 77)	52	24∗∗	9∗∗,##	3∗∗,###	0∗∗,###	0∗∗,###	0∗∗,###	0∗∗,###
SOC Group (n = 73)	56	37∗,$$	18∗∗,$	7∗∗	3∗∗	0∗∗	0∗∗	0∗∗
Nasal discharge
Add-on Group (n = 77)	0	0	0	0	0	0	0	0
SOC Group (n = 73)	6	2∗∗	0∗∗	0∗∗	0∗∗	0∗∗	0∗∗	0∗∗
Headache
Add-on Group (n = 77)	40	24	20	18	15	12	7∗,#	5∗,##
SOC Group (n = 73)	45	40$$	32$	26∗∗	23∗∗	20∗∗	15∗∗	13∗∗,$
Loss of taste
Add-on Group (n = 77)	9	2	0	0	0	0	0∗∗,###	0∗∗,###
SOC Group (n = 73)	12	4	2	0∗∗	0∗∗	0∗∗,###	0∗∗,###	0∗∗,###
Loss of smell
Add-on Group (n = 77)	0	0	0	0	0	0	0	0
SOC Group (n = 73)	4	0∗	0∗	0∗	0∗	0∗	0∗	0∗
Generalized weakness
Add-on Group (n = 77)	56	56	54	51	50	46	39	35∗,#
SOC Group (n = 73)	58	55	52	43	40	38∗	35∗,##	35∗,##
GIT symptoms
Add-on Group (n = 77)	21	11	5	0	0∗∗,###	0∗∗,###	0∗∗,###	0∗∗,###
SOC Group (n = 73)	25	18	11	7∗	5∗∗,#	3∗∗,##	0∗∗,###	0∗∗,###

∗p<0.01, ∗∗p<0.001 as compared to Day 1 using Kruskal Wallis test.

^#p<0.05, ^##p<0.01, ^###p<0.001 as compared to Day 7 using Kruskal Wallis test.

^@@@p < 0.001 as compared to Day 14 using Kruskal Wallis test.

^$p<0.05, ^$$p<0.01 as compared to Add-on Group using unpaired t test with Welch correction.