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. 2021 Dec 13;15(2):327–337. doi: 10.1038/s41385-021-00472-w

Fig. 2. Overexpression of HVEM partially modulates LIGHT-mediated gene expression in esophageal fibroblasts.

Fig. 2

qRT-PCR of: HVEM and LTβR (a); ICAM-1 and IL-32 (b); IL-34 (c); and DKK1, WNT2B and BMP6 (d), in normal esophageal fibroblasts transfected with empty vector (pCMV6-XL4), HVEM-OE (pCMV6-XL4-HVEM) or a combination of HVEM-OE + siLTβR, and untreated or treated with LIGHT (n ≥ 3). Each colored dot represents fibroblasts from a different donor, *p < 0.05, **p < 0.01 and ***p < 0.001.