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. 2022 Feb 10;13:822895. doi: 10.3389/fimmu.2022.822895

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Copyright © 2022 Liang, Greven, Qin, Fragoulis, Horst, Bläsius, Wruck, Pufe, Kobbe, Hildebrand and Lichte

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytokines secreted by Kupffer cells (n=6 in each group). The TNF-α (A), IL-6 (B), MCP-1(C), KC/CXCL1 (D), GM-CSF (E), and IL-10 (F) levels in C57/BL6 WT mouse plasma following HS/R or sham surgery with the HS/R + SFN group or sham + SFN group or without the administration of SFN (HS/R groups or sham groups). The results are expressed in pg/mL as mean ± SD. (*p < 0.05, **p < 0.01; the data of 6h group in graph (A) were analyzed by Kruskal-Wallis test followed by Dunn’s post hoc test, and others were obtained with use of one-way ANOVA followed by Tukey’s post hoc test).