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. 2022 Feb 10;12:698206. doi: 10.3389/fneur.2021.698206

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Copyright © 2022 Vaughn, Winston, Levin, Rissman and Risbrough.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exosome Release Schematic. EVs are released by neurons and glia. Their cargo often contains protein, cytokines, and/or miRNA. These exosomes can cross the blood brain barrier and enter the peripheral bloodstream, allowing for quantification and study. This figure was created using the Mind the Graph online platform (www.mindthegraph.com).