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. 2022 Feb 10;13:813218. doi: 10.3389/fimmu.2022.813218

Figure 8.

Figure 8

Regulation of dNK cells and EVT cells by CD39 and CD73. CD39 and CD73 hydrolyze ATP to adenosine changed dNK cells cytotoxicity, apoptosis, cytokine production, and impaired invasion of EVT cells. TGF-β induces the expression of CD73 on the EVT cells via mTOR-HIF-1α pathway.