Table 1.

Characteristics of the total enrolled study sample and the analytical study sample

Characteristic	Enrolled study sample	Analytical study sample*
Sex, % (n/total)
Male	51.2 (786/1,536)	50.4 (696/1,381)
Female	48.8 (750/1,536)	49.6 (685/1,381)
FLG genotype, % (n/total)
Loss-of-function	10.3 (118/1,150)	10.3 (116/1,129)
Maternal eczema, % (n/total)
Yes	12.1 (147/1,213)	12.1 (144/1,191)
Paternal eczema, % (n/total)
Yes	6.4 (78/1,213)	6.5 (77/1,191)
Birthweight, % (n/total)
Low/normal†	88.0 (1,329/1,511)	87.6 (1,192/1,360)
High‡	12.0 (182/1,511)	12.4 (168/1,360)
Birth order, % (n/total)
First	42.1 (510/1,212)	42.0 (500/1,189)
Second	34.6 (419/1,212)	34.5 (410/1,189)
Third or more	23.3 (283/1,212)	23.5 (279/1,189)
Household cat at birth, % (n/total)
Yes	32.4 (492/1,516)	32.6 (448/1,374)
Household dog at birth, % (n/total)
Yes	29.0 (440/1,516)	28.8 (396/1,374)
Breastfeeding duration, Median (IQR)
Weeks	8.0 (1.0-26.0)	9.0 (2.0-28.0)

IQR: interquartile range.

^*Includes participants who have three or more valid eczema status information (i.e., not missing) across the five analytical follow-ups.

^†Low/normal birthweight: <4000 grams.

^‡High birthweight: ≥4000 grams