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. 2022 Feb 10;12:820126. doi: 10.3389/fimmu.2021.820126

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Copyright © 2022 Portillo, Fedeli, Ustero Alonso, Petignat, Mereles Costa, Sulstarova, Jaksic, Yerly and Calmy

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Quantification of anti-RBD Ig (GMT) in HIV-1 undetectable patients (≤20 copies/ml, blue dots) and HIV-1 detectable patients (>20 copies/ml, green dots) at each time point. ns = not significant (P-value >0.05). (B) Log-transformed values of HIV-1 RNA levels at each time point. Average values (red) and standard deviations (blue) were calculated only using detectable HIV-1 RNA levels (>20 copies/ml). Differences are not statistically significant (P>0.05). RBD, receptor binding domain; GMT, geometric mean titers; M0, at the first dose; M1, 30 days after the first vaccine dose; M2, 60 days after the first vaccine dose; M6, 6 months after the first vaccine dose.