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. 2020 Sep 6;272(2):187–198. doi: 10.1007/s00406-020-01189-w

Table 2.

Scores obtained at the ADOS-2 and ADI-R

ADOS-2, median (range) Total (n = 138) Males (n = 96) Females (n = 42) U/χb rc p value Adj p value
Communication 3 (0–8) 3 (0–8) 2 (0–6) 1582 0.18 0.038 0.11
Social interaction 6 (2–14) 6 (2–14) 5 (2–11) 1272.5 0.30 0.001 0.008
Communication + Social interaction 9 (2–20) 9 (2–20) 7 (2–16) 1324.5 0.27 0.001 0.006
Imagination/Creativity 1 (0–2) 1 (0–2) 0.5 (0–2) 1620 0.17 0.05 0.11
RRB 1 (0–4) 1.5 (0–4) 1 (0–4) 1400.5 0.25 0.003 0.01
ADOS-2 above the cutoffsa, n (%) 124 (89.8) 93 (96.9) 31 (73.8) 17.05 0.35  < 0.001  < 0.001
ADI-R, median (range) Total (n = 130) Males (n = 93) Females (n = 37) U/χb r/φc p-value Adj p-value
Social Interaction 12 (1–30) 13 (1–30) 10 (4–27) 1407 0.14 0.10 0.18
Communication 9 (3–22) 9 (4–22) 9 (3–21) 1337 0.17 0.05 0.10
RRB 5 (1–12) 5 (1–12) 4 (1–11) 1269 0.21 0.02 0.08
Developmental abnormalities 1 (0–5) 2 (0–5) 1 (0–5) 1478.5 0.11 0.20 0.29
ADI-R above the cutoffsb, n (%) 75 (54.3) 59 (61.5) 16 (38.1) 4.42 0.18 0.03 0.11

ADOS-2 Autism diagnostic Observation Schedule-2, ADI-R Autism Diagnostic Interview–Revised, Adj p value Benjamini–Hochberg adjusted p value, C + SI Communication + Social interaction, RRB restricted interests and repetitive behaviors. Significant p values and adjusted p values are marked in bold

aADOS-2: A subject met the cutoff values for the autism spectrum if scores were 2 or above in the Communication domain, 4 or above in the Social Interaction domain, and 7 or above in the Communication + Social Interaction domain

bADI-R: A subject met the cutoff values for autism if scores were 10 or above in the Social Interaction domain, 8 or above in the Communication domain (7 for non-verbal subjects), and 3 or above in the RRB domain