Table 2.
ADOS-2, median (range) | Total (n = 138) | Males (n = 96) | Females (n = 42) | U/χb | r/φc | p value | Adj p value |
---|---|---|---|---|---|---|---|
Communication | 3 (0–8) | 3 (0–8) | 2 (0–6) | 1582 | 0.18 | 0.038 | 0.11 |
Social interaction | 6 (2–14) | 6 (2–14) | 5 (2–11) | 1272.5 | 0.30 | 0.001 | 0.008 |
Communication + Social interaction | 9 (2–20) | 9 (2–20) | 7 (2–16) | 1324.5 | 0.27 | 0.001 | 0.006 |
Imagination/Creativity | 1 (0–2) | 1 (0–2) | 0.5 (0–2) | 1620 | 0.17 | 0.05 | 0.11 |
RRB | 1 (0–4) | 1.5 (0–4) | 1 (0–4) | 1400.5 | 0.25 | 0.003 | 0.01 |
ADOS-2 above the cutoffsa, n (%) | 124 (89.8) | 93 (96.9) | 31 (73.8) | 17.05 | 0.35 | < 0.001 | < 0.001 |
ADI-R, median (range) | Total (n = 130) | Males (n = 93) | Females (n = 37) | U/χb | r/φc | p-value | Adj p-value |
---|---|---|---|---|---|---|---|
Social Interaction | 12 (1–30) | 13 (1–30) | 10 (4–27) | 1407 | 0.14 | 0.10 | 0.18 |
Communication | 9 (3–22) | 9 (4–22) | 9 (3–21) | 1337 | 0.17 | 0.05 | 0.10 |
RRB | 5 (1–12) | 5 (1–12) | 4 (1–11) | 1269 | 0.21 | 0.02 | 0.08 |
Developmental abnormalities | 1 (0–5) | 2 (0–5) | 1 (0–5) | 1478.5 | 0.11 | 0.20 | 0.29 |
ADI-R above the cutoffsb, n (%) | 75 (54.3) | 59 (61.5) | 16 (38.1) | 4.42 | 0.18 | 0.03 | 0.11 |
ADOS-2 Autism diagnostic Observation Schedule-2, ADI-R Autism Diagnostic Interview–Revised, Adj p value Benjamini–Hochberg adjusted p value, C + SI Communication + Social interaction, RRB restricted interests and repetitive behaviors. Significant p values and adjusted p values are marked in bold
aADOS-2: A subject met the cutoff values for the autism spectrum if scores were 2 or above in the Communication domain, 4 or above in the Social Interaction domain, and 7 or above in the Communication + Social Interaction domain
bADI-R: A subject met the cutoff values for autism if scores were 10 or above in the Social Interaction domain, 8 or above in the Communication domain (7 for non-verbal subjects), and 3 or above in the RRB domain