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. 2022 Feb 23;12:3039. doi: 10.1038/s41598-022-06766-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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TMS strategy for patient presenting with moderate expressive aphasia secondary to glioblastoma. (a) Preoperative MRI (left) demonstrating left insula glioblastoma and postoperative MRI (right) demonstrating complete resection. (b) Network analysis demonstrating a strongly organized posterior temporal region that is not in in the same network as Broca’s area. This was the area that was selected for treatment with iTBS. (c). Further network analysis demonstrating Broca’s area with bilateral representation that is not in the same network as the posterior temporal region.