Table 1.
Demographic, anthropometric, medication history and biochemical variables in CAD cases and healthy controls.
| Parameters | CAD Cases (n = 53) | Controls (n = 42) | p value |
|---|---|---|---|
| Age (years) | 52.70 ± 5.4 | 49.00 ± 6.3 | 0.003 |
| BMI (Kg/m2) | 23.70 ± 4.1 | 26.07 ± 3.4 | 0.004 |
| Gender (n %) | M (44; 83.0%) F (09; 16.9%) | M (34; 80.9%) F (8; 19.0%) | 0.794 |
| Family history | |||
| CVD (n %) | 11; 20.75% | 06; 14.29% | 0.414 |
| Diabetes (n%) | 19; 35.85% | 08; 19.00% | 0.071 |
| Hypertension (n %) | 30; 56.00% | 5; 11.90% | < 0.0001 |
| Dyslipidemia (n %) | 02; 3.70% | 07; 16.60% | 0.033 |
| Lifestyle factors | |||
| Smoking (n %) | 18; 33.96% | 08; 19.0% | 0.105 |
| Alcohol (n %) | 13; 24.53% | 08; 19.0% | 0.523 |
| Medication history | |||
| ACE Inhibitor (n %) | 23 (43.4%) | Nil | |
| β-Blocker (n %) | 45 (84.9%) | Nil | |
| Statin (n %) | 46 (86.7%) | Nil | |
| Aspirin (n %) | 47 (88.6%) | Nil | |
| Ca2 + Channel Blocker (n %) | 08 (15.0%) | Nil | |
| Diuretics (n %) | 10 (18.8%) | Nil | |
| Nitrate (n %) | 38 (71.7%) | Nil | |
| Baseline biochemical parameters | |||
| Fasting Blood Glucose (mg/dl) | 111 (104—123) | 105 (96—121) | 0.084 |
| Total Cholesterol (TC) (mg/dl) | 126.0 ± 36.1 | 186.8 ± 49.3 | < 0.0001 |
| Triglyceride (mg/dl) | 98.0 (65—133) | 157.5 (121—213) | < 0.0001 |
| HDL cholesterol (mg/dl) | 36.0 ± 9.4 | 41.7 ± 9.0 | 0.003 |
| LDL cholesterol (mg/dl) | 76.1 ± 27.2 | 113.6 ± 32.6 | < 0.0001 |
| VLDL cholesterol (mg/dl) | 12.0 (9.0 – 16.0) | 24.6 (16.8 – 39.0) | < 0.0001 |
| TC: HDL | 3.56 ± 0.82 | 4.48 ± 0.84 | < 0.0001 |
| LDL: HDL | 2.15 ± 0.68 | 2.72 ± 0.59 | < 0.0001 |
| Creatinine (mg/dl) | 0.74 ± 0.18 | 0.71 ± 0.15 | 0.464 |
Data expressed as mean ± standard deviation for normally distributed data and as median and interquartile range (IQR) for non-normally distributed data. Categorical variables were represented in percentage. Unpaired t-test and Mann Whitney test U was performed for normally and non-normally distributed data and Chi2 test for categorical variables respectively. p values ≤ 0.05 was considered statistically significant.