Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 23;12:3074. doi: 10.1038/s41598-022-05164-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Effects of miR-298 treatment on APP and BACE1 mRNA in astrocytes and differentiated neuroblastoma cells. (a, b) Astrocytes were transfected with miR-298 for 3 days. RNA was harvested for reverse transcription and following quantification by real-time qPCR. APP and BACE1 mRNA showed significant reduction when transfected with miR-298. (c,d) Real-time qPCR analysis in differentiated neuroblastoma cells transfected with miR-298. (e) Quantification of endogenous miR-298 levels in astrocytes U373 and NBRA differentiated SK-N-SH. MiR-298 levels were normalized with the geometric means of miR-16, RNU48 and RNU6B. Significant pairwise difference indicated by "*".