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. 2022 Feb 23;12:3055. doi: 10.1038/s41598-022-06971-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Model calibration. (A) Age distributions of cumulative numbers of confirmed cases in California Department of Public Health data (red) and clinical cases estimated from the model (turquoise) up to October 22, 2020. (B) Age distributions of infections estimated from seroprevalence estimates for California up to October 8–13, 2020, from CDC nationwide commercial lab seroprevalence data (red)²⁸ and estimated from the model using the infection fatality rate (IFR) from²⁶ recalibrated for California such that the total numbers of cases in the distributions in (A) match.