Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 23;12:3056. doi: 10.1038/s41598-022-06848-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fer-1 downregulates ferroptosis markers in PAECs. (A) Representative images showing the effect of Fer-1 on the expression of ferroptosis-related proteins (NOX4, GPX4 and FTH1) in PAECs, as assessed by western blot analysis. The group of blots were cropped from the same gel. (B–D) Bar graph showing that Fer-1 treatment significantly restored ferroptosis-related proteins (NOX4, GPX4 and FTH1) in PAECs. Quantitative western blot results were normalized to GAPDH. NC, normal control group; Model, model group; Fer-1, MCT + Fer-1 (10 nM) group. Each experiment was repeated 3 times, n = 3. The data represent the means ± SD. *P < 0.05 versus the NC group, #P < 0.05 versus the model group.