Table 2.
Characteristics of 68 adult offspring diagnosed with colorectal cancer, by age at diagnosis
| Age 18 – 49 years (n=33) | Age 50 – 56 years (n=35) | |||
|---|---|---|---|---|
| n | (%) | n | (%) | |
| Sex | ||||
| Male | 14 | (42.4) | 17 | (48.6) |
| Female | 19 | (57.6) | 18 | (51.4) |
| Year of birth | ||||
| 1959–61 | 10 | (30.3) | 18 | (51.4) |
| 1962–64 | 19 | (57.6) | 14 | (40.0) |
| 1965–67 | 4 | (12.1) | 3 | (8.6) |
| Race/ethnicity | ||||
| Non-Hispanic White | 19 | (57.6) | 16 | (50.0) |
| Non-Hispanic Black | 13 | (39.4) | 6 | (18.8) |
| Hispanic | 0 | (0.0) | 5 | (15.6) |
| Asian | 0 | (0.0) | 3 | (9.4) |
| Other | 1 | (3.0) | 2 | (6.3) |
| Missing | 0 | 3 | ||
| Age at diagnosis (years) | ||||
| Median (IQR) | 44 | (40 – 48) | 52 | (51 – 53) |
| Year of diagnosis | ||||
| 1980–89 | 2 | (6.1) | 0 | (0.0) |
| 1990–99 | 3 | (9.1) | 0 | (0.0) |
| 2000–09 | 17 | (51.5) | 0 | (0.0) |
| 2010–16 | 11 | (33.3) | 35 | (100.0) |
| Stage at diagnosis | ||||
| Local | 6 | (18.2) | 13 | (39.4) |
| Regional | 19 | (57.6) | 11 | (33.3) |
| Distant | 8 | (24.2) | 9 | (27.3) |
| Missing | 0 | 2 | ||
| Tumor location | ||||
| Proximal colon | 7 | (21.9) | 12 | (35.3) |
| Distal colon | 19 | (59.4) | 9 | (26.5) |
| Rectum | 6 | (18.8) | 13 | (38.2) |
| Missing | 1 | 1 | ||
| Family history of CRC2 | ||||
| No | 27 | (81.8) | 29 | (82.9) |
| Yes | 6 | (18.2) | 6 | (17.1) |
1
Stage at diagnosis defined by SEER summary stage and includes: local (disease is confined to the large bowel), regional (disease is limited to nearby lymph nodes or other organs), and distant (systemic metastasis)
2
Family history of CRC defined as having a mother or father ever diagnosed with CRC and ascertained by linking maternal and paternal records to the California Cancer Registry