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. 2022 Feb 10;13:760776. doi: 10.3389/fimmu.2022.760776

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Copyright © 2022 Majewski, Szewczyk, Jerczyńska, Miłkowska-Dymanowska, Białas, Gwadera and Piotrowski

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Associations of changes in serum CHIT1 activity and YKL-40 concentration with changes in FVC% pred. in patients with the stable and progressive disease over the second year of antifibrotic treatment. Panels showing: (A) a correlation between changes in serum YKL-40 concentration levels and changes in FVC% pred. in the stables subgroup (n=15), (B) a correlation between changes in serum CHIT1 activity levels and changes in FVC% pred. in the progressors subgroup (n=10), FVC, forced vital capacity; CHIT1, chitotriosidase; YKL-40, chitinase 3-like-1.