Table 1.
Baseline characteristics of the study population.
| Controls | IPF | |
|---|---|---|
| Number of subjects | 20 | 25 |
| Sex (male/female) | 10/10 | 14/11 |
| Age (years), mean (SD) | 68.40 (6.11) | 68.53 (8.03) |
| Smoking history (pack-years), median (IQR) | 2.55 (0-36.13) | 20.00 (0-30) |
| Smoking status | ||
| - never smokers, n (%) | 9 (45.00%) | 7 (28.00%) |
| - ex-smokers, n (%) | 3 (15.00%) | 17 (68.00%) |
| - current smokers, n (%) | 8 (40.00%) | 1 (4.00%) |
| CPI score, mean (SD) | N/A | 69.64 (7.17) |
| Time since diagnosis (years), median (IQR) | N/A | 1.58 (0.59-3.65) |
| FVC (l), mean (SD) | 3.88 (1.21) | 2.58 (0.85)*** |
| FVC (% of predicted), mean (SD) | 111.30 (20.73) | 73.35 (19.11)**** |
| TL,CO (mmol/min/kPa), mean (SD) | N/A | 3.91 (1.12) |
| TL,CO (% of predicted), mean (SD) | N/A | 52.50 (13.22) |
| 6MWT (meters), mean (SD) | N/A | 388.00 (102.10) |
***p < 0.001; ****p < 0.0001.
IPF, idiopathic pulmonary fibrosis; CPI, composite physiologic index; FVC, forced vital capacity; TL,CO, transfer factor of the lung for carbon monoxide; 6MWT, six-minute walk test.