Figure 1.

Significant improvement in cognitive performance, which can only partly be explained by the effect on depression. Alteration of the cognitive performance and depression status of participants with HD after starting administration of cariprazine. (A) Line plot shows the difference in individual points scored by Beck's Depression Inventory (0–63) compared to the baseline and 8 and 12th weeks, respectively. Next to the diagram, all of the participating patients are listed in the order of the largest difference in observed change over the observation period. The baseline points in brackets, followed by change at the 12th week is shown. (B) Line plot for Addenbrook's Cognitive Examination (ACE) questionnaire (0–100). On both diagrams, the color intensity of the lines is proportional with the severity on the depression scale in a similar way.