TABLE 1.
Baseline demographics.
| Placebo (n = 7) | 50 mg (n = 3) | 100 mg (n = 6) | 200 mg (n = 6) | 400 mg (n = 6) | All subjects (n = 28) | |
|---|---|---|---|---|---|---|
| Age (years) | ||||||
| Mean (SD) | 31.7 (7.2) | 35.0 (4.4) | 31.3 (10.8) | 32.7 (7.9) | 25.5 (3.0) | 30.9 (7.6) |
| Median (range) | 33.0 (19–40) | 33.0 (32–40) | 30.5 (21–43) | 33.5 (22–40) | 26.0 (22–29) | 29.0 (19–43) |
| Gender, n (%) | ||||||
| Male | 6 (85.7) | 2 (66.7) | 5 (83.3) | 3 (50.0) | 5 (83.3) | 21 (75.0) |
| Female | 1 (14.3) | 1 (33.3) | 1 (16.7) | 3 (50.0) | 1 (16.7) | 7 (25.0) |
| Weight (kg) | ||||||
| Mean (SD) | 69.8 (6.3) | 66.7 (6.6) | 60.5 (8.8) | 67.4 (6.7) | 60.5 (4.9) | 65.0 (7.5) |
| Median (range) | 69.3 (61.6–79.8) | 63.4 (62.5–74.3) | 56.7 (54.0–77.5) | 64.8 (62.6–80.1) | 59.8 (54.8–69.7) | 63.0 (54.0–80.1) |
| Height (cm) | ||||||
| Mean (SD) | 170.0 (5.7) | 162.0 (10.2) | 169.3 (2.9) | 167.5 (7.0) | 173.2 (4.9) | 169.1 (6.3) |
| Median (range) | 172.0 (159–176) | 164.0 (151–171) | 169.5 (165–174) | 163.5 (162–177) | 173.5 (165–180) | 170.0 (151–180) |
| BMI (kg/m2) | ||||||
| Mean (SD) | 24.2 (1.9) | 25.5 (2.3) | 21.1 (2.9) | 24.0 (1.5) | 20.2 (1.6) | 22.8 (2.7) |
| Median (range) | 25.1 (20.3–25.8) | 25.4 (23.2–27.8) | 20.3 (19.1–26.8) | 23.9 (21.5–25.7) | 19.8 (18.7–23.3) | 23.4 (18.7–27.8) |
| Alcohol use, n (%) | ||||||
| Never | 7 (100.0) | 3 (100.0) | 6 (100.0) | 6 (100.0) | 6 (100.0) | 28 (100.0) |
| Smoking history, n (%) | ||||||
| Never | 6 (85.7) | 3 (100.0) | 5 (83.3) | 6 (100.0) | 6 (100.0) | 26 (92.9) |
| Former | 1 (14.3) | 0 | 1 (16.7) | 0 | 0 | 2 (7.1) |
| Current | 0 | 0 | 0 | 0 | 0 | 0 |
Data are n (%) unless otherwise specified.