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. 2022 Feb 10;15:806713. doi: 10.3389/fnins.2021.806713

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Copyright © 2022 Khan, Nazir, Farooq, Khan and Javed.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Drug release and entrapment efficiency has been analyzed with HPLC. (A) Histogram representing diosgenin release from solid lipid nanoparticles after an hour. Bars show concentration-dependent diosgenin release. (B) Pie chart representing percent concentrations of diosgenin present/entrapped in solid lipid nanoparticles, formulation solvent (unentrapped) and residue in syringe filter showing diosgenin is entrapped in solid lipid nanoparticles at higher concentration (56%) then in residue (25%) and solvent have the least concentration of diosgenin (19%).