TABLE 1.

Summary for organs that have been recreated using organ-on-a-chip models.

Organ	Main characteristic	References
Liver	Maintains physiologic properties;	Wikswo et al. (2013), Kimura et al. (2018), Lu and Radisic, (2021)
	Great regenerative properties;
Breast Tissue	Mainly used in cancer study and treatment;	Bano, (2017), Chen et al. (2018), Gao et al. (2020)
	Difficult to treat;
Pancreas	Mainly used in cancer and diabetes study;	Wu et al. (2018), De Miollis et al. (2019), Glieberman et al. (2019)
	Hard to treat due to small number of vessels;
Lungs	Bad regenerative properties;	Kimura et al. (2018), Lu and Radisic, (2021), Wang et al. (2021)
	Successful replication of functionality by modifying the pressure;
Brain	Complex due to functionality;	Vassanelli, (2011), Wikswo et al. (2013), Bang et al. (2019)
	Differs from person to person;
	Can be recreated by separating the soma and axons;
Blood	Multiple cell types;	Wikswo et al. (2013), Ramadan and Gijs, (2015), Mao et al. (2020), Mandrycky et al. (2021)
	OoC uses all cell types;
	Need for small chambers;