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. 2022 Feb 7;9:256–268. doi: 10.1016/j.toxrep.2022.01.011

Table 4.

Absolute and relative organ weights in SHRSP of both sexes given SOY or CAN diet for 8 weeks.

Organs Male
 Female
SOY CAN SOY CAN
Brain Absolute weight (g)§ 1.97 ± 0.02 1.96 ± 0.02 1.92 ± 0.01 1.92 ± 0.01
Relative weight (mg/g)§ 7.17 ± 0.25 7.76 ± 0.40 10.8 ± 0.16 11.4 ± 0.25
Heart Absolute weight (g)§ 1.48 ± 0.04 1.52 ± 0.04 0.78 ± 0.01 0.74 ± 0.01*
Relative weight (mg/g)§,†,¶ 5.24 ± 0.16b 5.97 ± 0.11a,* 4.34 ± 0.09c 4.38 ± 0.06c
Lung Absolute weight (g)§ 1.34 ± 0.20 1.06 ± 0.06 0.85 ± 0.01 0.85 ± 0.01
Relative weight (mg/g) 4.91 ± 0.79 4.07 ± 0.08 4.77 ± 0.09 5.03 ± 0.09
Spleen Absolute weight (g)§ 0.62 ± 0.02 0.62 ± 0.02 0.43 ± 0.02 0.41 ± 0.02
Relative weight (mg/g) 2.24 ± 0.06 2.41 ± 0.09 2.41 ± 0.07 2.45 ± 0.08
Liver Absolute weight (g)§,¶ 8.03 ± 0.12a 7.95 ± 0.21a 5.19 ± 0.08b 5.66 ± 0.11b,*
Relative weight (mg/g)§,† 28.4 ± 0.31c 31.2 ± 0.47b 29.2 ± 0.17c 33.5 ± 0.64a,*
Kidneys Absolute weight (g)§ 2.36 ± 0.04 2.30 ± 0.04 1.31 ± 0.02 1.29 ± 0.03
Relative weight (mg/g)§,† 8.34 ± 0.09b 9.08 ± 0.25a,* 7.33 ± 0.06c 7.66 ± 0.15c
Adrenal glands Absolute weight (mg) 48.9 ± 2.57 55.0 ± 2.78 51.3 ± 1.13 49.4 ± 0.95
Relative weight (mg/g)§ 0.17 ± 0.01 0.21 ± 0.02 0.29 ± 0.01 0.29 ± 0.01
Testes Absolute weight (g) 2.98 ± 0.04 2.86 ± 0.08 – –
Relative weight (mg/g) 10.6 ± 0.21 11.3 ± 0.34 – –
Epididymides Absolute weight (g) 0.98 ± 0.02 0.93 ± 0.03 – –
Relative weight (mg/g) 3.49 ± 0.09 3.64 ± 0.06 – –
Ovaries Absolute weight (mg) – – 66.2 ± 1.68 68.5 ± 2.38
Relative weight (mg/g) – – 0.30 ± 0.01 0.29 ± 0.01
Uterus Absolute weight (g) – – 0.39 ± 0.04 0.29 ± 0.01*
Relative weight (mg/g) – – 2.20 ± 0.20 1.71 ± 0.05*

SOY, 10 w/w% soybean oil diet (control); CAN, 10 w/w% canola oil diet.

Values are means ± SEMs of 10 animals.

§ and †, Significantly different between sexes and between diets, respectively (p<0.05, two way ANOVA).

, Interaction exists between the factors, sexes and diets (p<0.05, two way ANOVA).

Identical alphabetical letters (above SEMs) indicate the absence of significant differences between the groups (p>0.05, Tukey’s test).

*, Significantly different from the SOY group in each sex (p<0.05, unpaired t-test).