TABLE 1.
Minimum inhibitory concentrations (MIC) and interpretation for K. pneumoniae ST101 of human and animal origin determined by ETEST® with the exception of colistin MIC which were determined using the broth microdilution method.
| MIC (mg/L) | ||||||||||
| Hospital-associated | Broiler | Pig | ||||||||
|
| ||||||||||
| Antibiotic | IT0132A | IT0132R1 | IT0132R2 | BCR0495 | BCR0504 | BCR0133 | FE1669 | PS1684E | 1101124 | 1101433 |
| Ampicillin | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) |
| Cefotaxime | >32 (R) | >32 (R) | >32 (R) | >32 (R) | >32 (R) | >32 (R) | >32 (R) | >32 (R) | 0.032 (S) | 0.032 (S) |
| Cetriaxone | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | 0.032 (S) | 0.032 (S) |
| Ceftazidime | >256 (R) | >256 (R) | >256 (R) | 32 (R) | 24 (R) | 32 (R) | >256 (R) | 96 (R) | 0.094 (S) | 0.094 (S) |
| Ceftazidime-avibactam | 1 (S) | 1 (S) | 1 (S) | 0.5 (S) | 0.5 (S) | 0.5 (S) | >256 (R) | 0.032 (S) | 0.094 (S) | 0.094 (S) |
| Imipenem | 6 (R) | 4 (I) | 6 (R) | >32 (R) | 6 (R) | 6 (R) | >32 (R) | 0.25 (S) | 0.19 (S) | 0.125 (S) |
| Ciprofloxacin | >32 (R) | >32 (R) | >32 (R) | >32 (R) | >32 (R) | >32 (R) | >32 (R) | >32 (R) | 0.016 (S) | 0.023 (S) |
| Norfloxacin | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | >256 (R) | 0.125 (S) | 0.125 (S) |
| Amikacin | 24 (R) | 24 (R) | 24 (R) | 12 (R) | 6 (S) | 6 (S) | 8 (S) | 1.5 (S) | 1.5 (S) | 2 (S) |
| Gentamicin | 96 (R) | 128 (R) | 128 (R) | 192 (R) | 48 (R) | 64 (R) | 96 (R) | 0.25 (S) | 0.38 (S) | 0.38 (S) |
| Tobramycin | 32 (R) | 32 (R) | 32 (R) | 24 (R) | 8 (R) | 12 (R) | 32 (R) | 0.25 (S) | 0.38 (S) | 0.38 (S) |
| Trimethoprim-sulfamethoxazole | 2 (S) | 2 (S) | 2 (S) | >32 (R) | >32 (R) | >32 (R) | 0.125 (S) | >32 (R) | 0.5 (S) | 0.75 (S) |
| Colistin | ≤ 0.125 (S) | 0.5 (S) | 64 (R) | 0.25 (S) | 2 (S) | 0.25 (S) | 2 (S) | 0.25 (S) | 1 (S) | 64 (R) |
R, resistant; S, sensitive; I, intermediate.