TABLE 3.

Common metabolic pathways: List of all common metabolic pathways, commonly shared by both organisms (S. pneumoniae and Human).

S. no	Metabolic pathways	Pathway ids	Protein in pathways
1	ABC transporters	pw02010	97
2	Alanine, aspartate, and glutamate metabolism	spw00250	17
3	Amino acid related enzymes	spw01007	27
4	Amino sugar and nucleotide sugar metabolism	spw00520	35
5	Aminoacyl-tRNA biosynthesis	spw00970	84
6	Arachidonic acid metabolism	spw00590	1
7	Arginine and proline metabolism	spw00330	7
8	Arginine biosynthesis	spw00220	7
9	Ascorbate and aldarate metabolism	spw00053	11
10	Bacterial toxins	spw02042	4
11	Base excision repair	spw03410	9
12	Biotin metabolism	spw00780	5
13	Butanoate metabolism	spw00650	7
14	CD molecules	spw04090	1
15	Chaperones and folding catalysts	spw03110	18
16	Chloroalkane and chloroalkene degradation	spw00625	2
17	Chromosome and associated proteins	spw03036	29
18	Citrate cycle (TCA cycle)	spw00020	4
19	Cysteine and methionine metabolism	spw00270	21
20	Cytoskeleton proteins	spw04812	3
21	D-Glutamine and D-glutamate metabolism	spw00471	3
22	DNA repair and recombination proteins	spw03400	67
23	DNA replication	spw03030	15
24	DNA replication proteins	spw03032	25
25	Enzymes	spw01000	1
26	Exosome	spw04147	26
27	Fatty acid biosynthesis	spw00061	15
28	Folate biosynthesis	spw00790	9
29	Fructose and mannose metabolism	spw00051	20
30	Galactose metabolism	spw00052	27
31	Glutathione metabolism	spw00480	8
32	Glycerolipid metabolism	spw00052	10
33	Glycerophospholipid metabolism	spw00564	8
34	Glycine, serine, and threonine metabolism	spw00260	16
35	Glycolysis/Gluconeogenesis	spw00010	26
36	Glycosyltransferases	spw01003	6
37	Glyoxylate and dicarboxylate metabolism	spw00630	7
38	Homologous recombination	spw03440	21
39	Inositol phosphate metabolism	spw00562	4
40	Ion channels	spw04040	1
41	Lipid biosynthesis proteins	spw01004	12
42	Lysine degradation	spw00310	2
43	Membrane trafficking	spw04131	5
44	Messenger RNA biogenesis	spw03019	14
45	Mismatch repair	spw03430	18
46	Mitochondrial biogenesis	spw03029	27
47	Nicotinate and nicotinamide metabolism	spw00760	8
48	Nitrogen metabolism	spw00910	4
49	Non-coding RNAs	spw03100	74
50	Nucleotide excision repair	spw03420	8
51	One carbon pool by folate	spw00670	10
52	Other glycan degradation	spw00511	10
53	Oxidative phosphorylation	spw00190	18
54	Pantothenate and CoA biosynthesis	spw00770	11
55	Pentose and glucuronate interconversions	spw00040	9
56	Pentose phosphate pathway	spw00030	19
57	Peptidases and inhibitors	spw01002	38
58	Phenylalanine, tyrosine, and tryptophan biosynthesis	spw00400	18
59	Porphyrin and chlorophyll metabolism	spw00860	1
60	Prenyltransferases	spw01006	3
61	Prokaryotic defense system	spw02048	25
62	Propanoate metabolism	spw00640	12
63	Protein export	spw03060	14
64	Protein kinases	spw01001	10
65	Protein phosphatases and associated proteins	spw01009	3
66	Purine metabolism	spw00230	36
67	Pyrimidine metabolism	spw00240	30
68	Pyruvate metabolism	spw00620	22
69	RNA degradation	spw03018	10
70	RNA polymerase	spw03020	6
71	Riboflavin metabolism	spw00740	6
72	Ribosome	spw03011	63
73	Ribosome biogenesis	spw03009	52
74	Secretion system	spw02044	13
75	Selenocompound metabolism	spw00450	7
76	Sphingolipid metabolism	spw00600	6
77	Starch and sucrose metabolism	spw00500	40
78	Sulfur metabolism	spw00920	5
79	Sulfur relay system	spw04122	5
80	Taurine and hypotaurine metabolism	spw00430	4
81	Terpenoid backbone biosynthesis	spw00900	8
82	Thiamine metabolism	spw00730	13
83	Transcription factors	spw03000	41
84	Transcription machinery	spw03021	11
85	Transfer RNA biogenesis	spw03016	52
86	Translation factors	spw03012	14
87	Transporters	spw02000	264
88	Valine, leucine, and isoleucine biosynthesis	spw00290	11
89	Valine, leucine, and isoleucine degradation	spw00280	3
90	Vitamin B6 metabolism	spw00750	4