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. 2021 Dec 22;16:2111–2123. doi: 10.2147/CIA.S343057

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© 2021 Zhang et al.

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ROC curves of 18 potential biomarkers in young adult group vs old-age group. 18 potential biomarkers include LysoPC (20:1) (AUC=0.923), γ-aminobutyric acid (AUC=0.971), L-valine (AUC=0.983), L-threonine (AUC=1), aminoadipic acid (AUC=0.939), leukotriene F4 (AUC=0.965), taurocholic acid (AUC=0.746), serotonin (AUC=0.738), LysoPE (18:2) (AUC=1), succinic acid (AUC=0.979), glycocholic acid (AUC=0.982), cis-Aconitic acid (AUC=0.973), methionine sulfoxide (AUC=0.998), LysoPC (O-18:0) (AUC=1), LysoPC (20:4) (AUC=0.837), 9,10-DiHODE (AUC=0.92), 12,13- DHOME (AUC=0.948), and deoxycholic acid (AUC=0.7130).