TABLE 4.
Single and multiple regressions predicting Citrate Synthase activity after controlling for TSI, LOI, or age.
| Citrate synthase activity r2 (p-value) |
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| Marker | TSI | β (TSI) | LOI | β (LOI) | Age | β (Age) |
| VAT | 0.174 (0.030) | −0.418 | 0.432 (<0.001) | −0.657 | 0.277 (0.005) | −0.526 |
| Testosterone | ns | 0.296 | 0.170 (0.026) | 0.412 | 0.176 (0.023) | 0.420 |
| CRP | ns | −0.285 | 0.249 (0.013) | −0.499 | 0.184 (0.036) | −0.429 |
| VAT:total trunk CSA | 0.162 (0.038) | −0.402 | 0.435 (0.001) | −0.660 | 0.285 (0.004) | −0.534 |
| VAT:TLM | 0.264 (0.006) | −0.514 | 0.507 (0.001) | −0.712 | 0.376 (0.001) | −0.613 |
| VAT + CRP | 0.294 (0.044) | −0.479, −0.216 | 0.503 (0.002) | −0.546, −0.251 | 0.365 (0.017) | −0.449, −0.273 |
| VAT + Testosterone | 0.226 (0.053) | −0.370, 0.238 | 0.508 (0.001) | −0.592, 0.279 | 0.382 (0.004) | −0.456, 0.334 |
| VAT:total trunk CSA + CRP | 0.245 (0.022) | −0.529, −0.287 | 0.537 (0.001) | −0.571, −0.263 | 0.415 (0.008) | −0.494, −0.298 |
| VAT:total trunk CSA + Testosterone | 0.250 (0.037) | −0.396, 0.306 | 0.534 (0.001) | −0.606, 0.322 | 0.414 (0.002) | −0.483, 0.374 |
| VAT:TLM + CRP | 0.343 (0.023) | −0.533, −0.171 | 0.531 (0.001) | −0.599, −0.200 | 0.410 (0.009) | −0.515, −0.222 |
| VAT:TLM + Testosterone | 0.288 (0.020) | −0.460, 0.176 | 0.548 (0.001) | −0.642, 0.216 | 0.432 (0.001) | −0.525, 0.265 |
| IL-6 | ns | −0.382 | ns | −0.389 | 0.237 (0.019) | −0.486 |
| VAT + IL-6 | ns | −0.479, −0.399 | ns | −0.492, −0.326 | 0.412 (0.011) | −0.419, −0.457 |
Weighted least squares regressions predicting Citrate Synthase activity when controlling for TSI, LOI, or age. Non-significant r2 are not shown (non-significant = ns), but non-significant yet trending r2 are included. Standardized Beta weights are presented to demonstrate directionality of associations.
TSI, time since injury; LOI, level of injury; VAT, visceral adipose tissue; CRP, c-reactive protein; IL-6, interleukin 6; LM, lean mass; TLM, total lean mass; CSA, cross sectional area.