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. 2022 Feb 10;12:772707. doi: 10.3389/fphys.2021.772707

FIGURE 3.

FIGURE 3

Influence of HE-diet in obesity-prone and -resistant rat dams in filial generation 0 and 1 (F0/F1) on meal pattern, amylin sensitivity, and maternal behavior. Average meal size in kilocalories (A) and meal number (B) of pregnant and postpartum rat dams on chow or high energy (HE) diet on gestational day 7 (G7), G20 ± 1, postpartum day 4 (P4), P9, and P15 ± 1. (C–F) Food intake as percentage of baseline following a single dose subcutaneous amylin (20 μg/kg) or vehicle (saline) injection in rat dams on gestational day 11 ± 2, 30 min (C), 1 h (D), 2 h (E), and 24 h (F) after injection. (G–J) Pup retrieval test and 60 min maternal behavior home cage observation in dams on either chow or HE diet on P2 and P7. Latency to retrieve first pup, latency to retrieve all pups and latency to start nursing in minutes on P2 (G) and P7 (I). Total nursing and eating duration in minutes on P2 (I) and P7 (J). Data are represented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001. N = 10 in chow group, N = 14 in HE group.