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. 2022 Feb 10;12:772707. doi: 10.3389/fphys.2021.772707

FIGURE 5.

FIGURE 5

Influence of HE-diet in diet resistant (DR) and diet induced obese (DIO) rat dams in filial generation 3 (F3) on meal pattern, amylin sensitivity and maternal behavior. Average meal size in kilocalories (A) and meal number (B) of pregnant and postpartum DR and DIO rat dams on chow or high energy (HE) diet on G20, P4, P9, and P12. (C–F) Maternal behavior in DR and DIO dams on chow or HE diet on P2 or P7. Latency to retrieve first pup, latency to retrieve all pups and latency to start nursing in seconds on P2 (C) and P7 (E). Total duration in seconds of pup-related and dam-related behavior on P2 (D) and P7 (F). (G,H) Open field test in virgin DR and DIO rat dams around 9 weeks of age on chow. (G) Number of center zone entries divided into 3 bins, where one bin represents 5 min. (H) Total traveled distance in centimeter (cm) in virgin DR and DIO dams per bin. (I,J) OFT on P10 in DR and DIO rat dams on chow or HE diet. Number of center zone entries (I) and total traveled distance in centimeter (J) divided into 3 5-min bins. (K) Sucrose preference in percent of total liquid intake on P14–15 in DR and DIO rat dams on either chow or HE diet. Data are represented as mean ± SD. *P < 0.05. DR-chow (N = 10), DR-HE (N = 5), DIO-chow (N = 9), and DIO-HE (N = 5).