Table 1.
Demographic and Clinical Characteristic of Multiple Sclerosis Patients and Healthy Controls
| Group | TOT | M | F | Age (years) mean ± SD | EDSS median (min–max) | NfL (pg/mL) mean (min–max) | T2 lesion volume (mm3) mean ± SD |
|---|---|---|---|---|---|---|---|
| HC | 64 | 26 | 38 | 36.9 ± 12.8 | / | / | / |
| RR | 46 | 16 | 30 | 37.3 ± 11.7 | 1.5 (0–4) | 7.4 (2.4–13.9) | 6017.0 ± 7123.0 |
| PP | 10 | 7 | 3 | 58.0 ± 8.3 | 4 (2–6) | 11.0 (4.7–17.1) | 15,719.0 ± 13,402.0 |
| SP | 10 | 4 | 6 | 60.2 ± 5.5 | 6.1 (3.5–8) | 14.3 (7.9–23.8) | 16,431.0 ± 18,679.0 |
Demographic and clinical characteristics of MS patients (divided according to the clinical phenotype of the disease) and HCs.
EDSS, expanded disability status scale; F, female; HCs, healthy controls; M, male; max, maximum; min, minimum; MS, multiple sclerosis; NfL, neurofilament light polypeptide; PP, primary progressive MS patients; RR, relapsing remitting MS patients; SD, standard deviation; SP, secondary progressive MS patients; TOT, total.