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. 2022 Jan 24;298(3):101630. doi: 10.1016/j.jbc.2022.101630

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© 2022 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

CDCP1 is recycled via the endosome system.A, T47D cells expressing MET and CDCP1-myc were stimulated with HGF for 30 min and subjected to immunofluorescence analysis for CDCP1-myc and the indicated endosome markers. Insets are magnified views. The scale bar represents 10 μm and 2 μm (inset) B, ratios of CDCP1 colocalization with endosome markers. The mean ratios ± SD were obtained from five independent experiments. ∗∗∗p < 0.001; unpaired two-tailed t test. C, schematic model of our working hypothesis derived from this study.